Vivitrol Injection: Uses, Dosage, Side Effects, Warnings

can you drink on naltrexone

This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or heroin withdrawal change the dosage of any medicines without your doctor’s approval. Naltrexone is a prescription medication used to treat alcohol use disorder (AUD) and opioid use disorder (OUD) to reduce cravings and help control physiological dependence.

can you drink on naltrexone

From Mayo Clinic to your inbox

Studies show that people who are alcohol dependent are two to three times as likely to suffer from major depression or anxiety over their lifetime. When addressing drinking problems, it’s important to also seek treatment for any accompanying medical and mental health issues. A flexible approach to a dosing regimen may need to be employed in cases of supervisedadministration. Thus, patients may receive 50 mg of naltrexone hydrochloride tablets every weekdaywith a 100 mg dose on Saturday, 100 mg every other day, or 150 mg every third day. The degree ofblockade produced by naltrexone hydrochloride tablets may be reduced by these extended dosingintervals.

Naltrexone: Medication for Alcohol Use Disorder

For opioid dependence, treatment should be initiated with an initial dose of 25 mg of Naltrexone Hydrochloride tablets. It is advisable for patients taking naltrexone to carry a card detailing their use of this agent that can be shown to health care providers. Because naltrexone blocks opioid receptors, it can render opiate analgesics ineffective, which may be of practical clinical importance, especially in an emergency setting. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use.

Can You Overdose on Alcohol While Taking Naltrexone?

Naltrexone use for either opioid use disorder or alcohol use disorder can lead to withdrawal symptoms if you are still using narcotics (opioids). Naltrexone blocks the brain areas where narcotics and alcohol work. So, you should be careful not to take any narcotics while you are taking naltrexone. Do not take any cough medicine with codeine in it while you are taking naltrexone. Naltrexone can cause or worsen withdrawal symptoms in people who take narcotics. You must stop taking all narcotics 7 to 10 days before you start taking naltrexone.

Related treatment guides

When naltrexone is taken at home, it is usually taken once a day with or without food. When naltrexone is taken in a clinic or treatment center, it may be taken once a day, once every other day, once every third day, or once every day except Sunday. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not take more or less of it or take it more often than prescribed by your doctor.

can you drink on naltrexone

It is important to remember that not all people will respond to medications, but for a subset of individuals, they can be an important tool in overcoming alcohol dependence. Research shows that about one-third of people who are treated for alcohol problems have no further symptoms 1 year later. Many others substantially reduce their drinking and report fewer alcohol-related problems. Many people struggle with controlling their drinking at some time in their lives. More than 14 million adults ages 18 and older have alcohol use disorder (AUD), and 1 in 10 children live in a home with a parent who has a drinking problem. The drug is reported to be of greatest use in good prognosis opioid addicts who take the drug as partof a comprehensive occupational rehabilitative program, behavioral contract, or other complianceenhancingprotocol.

  1. The pill form is taken daily and the extended-release injectable is administered every four weeks, or once a month, by a practitioner.
  2. Vivitrol is a long-acting injectable form of naltrexone, which is a medication used to treat two substance use disorders – opioid use disorder and alcohol use disorder (alcoholism).
  3. Tell your family members or other people close to you that you are taking naltrexone.
  4. Your health care provider or mental health provider will ask additional questions based on your responses, symptoms and needs.
  5. Low dose naltrexone (LDN) is used for conditions such as fibromyalgia, Crohn’s disease, multiple sclerosis, and complex regional pain syndrome, as it may work as an anti-inflammatory agent in the central nervous system.
  6. While the oral formulation will also block opioid receptors, only the long-acting injectable formulation is FDA approved as a medication for OUD.


I’ve seen many people successfully cut out or curb their drinking with medication and without it. It’s all about finding a treatment plan that works for you and gives you the support that you need. The case presented here is a fairly typical example of a heavy drinker 6 steps to quit drinking on your own who is mildly to moderately dependent on alcohol. Since his condition does not appear to be severe, the practitioner could offer brief advice to reduce or stop drinking with monitoring of blood tests and blood-pressure measurement during a period of 2 to 4 weeks.

Sudden opioid withdrawal can be severe, and you may need to go to the hospital. Using opioids in the 7 to 14 days before you start receiving treatment may cause you to suddenly have symptoms of opioid withdrawal when you receive drugs brains and behavior treatment. Naltrexone limits your ability to feel rewarding or pleasurable effects after drinking alcohol, and thus reduces your craving for it. The way naltrexone treatment works is by altering what alcohol does to your brain.

An opioid-free interval of a minimum of 7 to 10 days is recommended forpatients previously dependent on short-acting opioids. Patients transitioning from buprenorphine ormethadone may be vulnerable to precipitation of withdrawal symptoms for as long as two weeks. An opioid-free interval of a minimum of 7 to 10 days is recommendedfor patients previously dependent on short-acting opioids. Using opioids in the 7 to 14 days before you start receiving Vivitrol may cause you to suddenly have symptoms of opioid withdrawal when you get your injection.

Alcohol use disorder (AUD) is a medical condition that doctors diagnose when a patient’s drinking causes distress or harm. The condition can range from mild to severe and is diagnosed when a patient answers “yes” to two or more of the following questions. You are encouraged to report negative side effects of prescription drugs to the FDA.

They may change your treatment or suggest ways you can deal with the side effects. Taking 25 mg of naltrexone is not considered an effective dose for AUD and has not been well studied. To learn more about some of the key reasons you may not be familiar with medication-assisted treatment for AUD, see the Reference Library section below. Get articles and stories about health, wellness, medicine, science and education delivered right to your inbox from the experts at Ohio State.

Below is a list of providers and the type of care they may offer. When asked how alcohol problems are treated, people commonly think of 12-step programs or 28-day inpatient rehab but may have difficulty naming other options. In fact, there are a variety of treatment methods currently available, thanks to significant advances in the field over the past 60 years. There are no data that demonstrate an unequivocally beneficial effect of naltrexone hydrochloride onrates of recidivism among detoxified, formerly opioid-dependent individuals who self-administer thedrug.

We understand that finding the right approach to change your drinking habits can be challenging, and we’re here to connect you to expert clinicians to guide you along the way. At Monument, you can connect with a physician online to discuss if medication to stop drinking is right for your recovery journey, and get ongoing care. In contrast, another medication used to treat alcohol use disorder, disulfiram, increases alcohol sensitivity when consumed. This increased sensitivity can cause you to become very ill, as disulfiram causes the same effects of a hangover almost immediately after alcohol is ingested. You might be wondering what it feels like to take naltrexone and drink alcohol.

can you drink on naltrexone

While naltrexone therapy can be effective alone, many people see the greatest benefit when combining medication assisted treatment with counseling and behavioral therapies. Also, if naltrexone isn’t right for you, you might explore other medication options such as disulfiram. To reduce the risk of withdrawal symptoms caused by OUD, patients should wait at least 7 days after their last use of short-acting opioids and 10 to 14 days for long-acting opioids, before starting naltrexone.

Do not take this medicine within 7 to 10 days of taking any opioid drugs. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Talk to your physician for guidance, or for more information on the safe disposal of unused medications, visit FDA’s disposal of unused medicines or DEA’s drug disposal webpages.

There was limited evidence of a weak genotoxic effect of naltrexone in one gene mutation assay in amammalian cell line, in the Drosophila recessive lethal assay, and in non-specific DNA repair tests withE-coli. Naltrexone did not exhibit clastogenicityin an in-vivo mouse micronucleus assay. Naltrexone hydrochloride does not interfere with thin-layer, gas-liquid, and high pressure liquidchromatographic methods which may be used for the separation and detection of morphine, methadoneor quinine in the urine.

Haider Sultan

I'm a qualified content writer for Peak Searchers, and I'm eager to produce articles about tech-related topics. My primary occupation is not writing, but I still regard it as a hobby and a love. I've been writing content as a job for a while now.

Leave a Reply

Your email address will not be published.